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Top Innovative Digital Therapeutics Companies of 2022

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Top Innovative Digital Therapeutics Companies of 2022

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  • Transforming lives by leveraging cutting-edge technological advances, digital health companies have embarked on a journey to reshape the way we see and experience therapeutics
  • Digital health companies are fostering the use of highly innovative technologies in the healthcare system. In 2021, the global digital health therapeutics market was valued at $3.8B and is envisioned to reach $22.6B by 2031
  • PharmaShots presents a concise and informative report on the Top Innovative Digital Therapeutics Companies of 2022

 

Founded Year: 2011

Total Employees: ~50

Headquarters: Washington, United States

Therapy Areas: Neurology

2Morrow develops and delivers evidence-based behavioral change programs through smartphone apps by integrating technology and behavioral science. The company offers three programs, viz. Wellbeing Bundle, Resolve Bundle, and Breathe Bundle, developed by the combination of multiple interconnected programs. 2Morrow's programs mainly focus on, Smoking & Tobacco Cessation, Vaping Cessation, Quitting Tobacco while Pregnant, Weight Management, Stress or Anxiety Management, and Chronic Pain. On Mar 2022, the results from 2Morrow’s observational study conducted in collaboration with the Washington State Department of Health to assess the company's Cessation app among 1280 adult Washington state residents were published in JMIR Public Health and Surveillance.

 

Founded Year: 2011

Total Employees: ~250

Headquarters: Massachusetts, United States

Therapy Areas: Neurology

By merging neuroscience with entertainment and modern technology, Akili focuses on developing personalized digital solutions to improve cognitive impairments. The company develops therapies in the form of interactive action video games using neuroscience data and proprietary technology. EndeavorRx is the company’s first US FDA-approved video game developed as a therapeutic option for the treatment of children (aged 8-12) with ADHD. In Jan 2022, Akili signed a reverse merger worth $1B with Social Capital Suvretta Holdings Corp. (SPAC) to convert the company into a public organization.   

 

Founded Year: 2015

Total Employees: ~50

Headquarters: California, United States

Therapy Areas: Cardiovascular, Metabolic

Better Therapeutics develops Prescription Digital therapeutics to advance human health through behavior change. The company primarily focuses on developing treatment options for multiple therapy areas, including Type 2 Diabetes, Hypertension, Hyperlipidemia, Non-Alcoholic Fatty Liver Disease, Non-Alcoholic Steatohepatitis, and chronic kidney disease. Behavioral Therapy, Treatment Plans, and Personalization are the three platforms under which the company discovers and delivers treatment plans. In Sep 2022, Better submitted a De Novo Request to the US FDA to receive the marketing authorization for BT-001 to treat Type 2 Diabetes in patients aged ≥18yrs.

 

Founded Year: 2015

Total Employees: ~570

Headquarters: Massachusetts, United States

Therapy Areas: Neurology, Cardiology, Respiratory, Oncology

A digital health company, Biofourmis develops and delivers personalized digital care to patients with chronic conditions under therapy areas, including Neurology, Cardiology, Respiratory, and Oncology. The company delivers therapeutics under two divisions viz. Biofourmis Connect and Biofourmis Care. Biovitals is the company’s US FDA-approved machine-learning and AI-approved medical device for ambulatory physiological monitoring. In Aug 2022, Biofourmis reported the joining of Intel Capital into its ongoing Series D funding (raising the value to $320M), initiated in April 2022 and led by General Atlantic with the participation of CVS Health. 

 

Founded Year: 2011

Total Employees: ~330

Headquarters: Massachusetts, United States

Therapy Areas: Multiple

With a business focused on digital health, Butterfly Network develops and delivers diagnostic and therapeutic imaging devices to yield better clinical outcomes. The company provides easy-to-use medical imaging techniques developed using ultrasound technology and artificial intelligence. Butterfly iQ+ is Butterfly Network’s approved ultrasound device with the ability to perform whole-body imaging in a single handheld probe using semiconductor technology. In May 2022, Butterfly Network joined forces with Petco Health and Wellness Company to deploy Butterfly iQ+ Vet to around 200 full-service veterinary hospitals at Petco pet care centers.

 

Founded Year: 2012

Total Employees: ~160

Headquarters: New York, United States

Therapy Areas: Psychiatry, Neurology, Oncology, Cardiology, Immunology

With expertise in developing software for medical therapeutics, Click Therapeutics is a renowned name in providing digital solutions for patients with unmet medical needs. The company tailors cognitive and neurobehavioral mechanisms to provide digital therapeutics designed to be used alone or in conjugation with biomedical treatments. Psychiatry, Neurology, Oncology, Cardiology, and Immunology are the major therapy areas for which the company is currently developing digital therapeutics. In Dec 2022, Click Therapeutics received the Breakthrough Device Designation from the US FDA for the treatment of episodic migraine.

 

Founded Year: 2013

Total Employees: ~200

Headquarters: California, United States

Therapy Areas: Neurology

A pediatric behavioral healthcare company, Cognoa develops and delivers digital diagnostics and therapeutics for the early diagnosis and treatment of behavioral health conditions. The company leverages AI to advance the efficacy of its medical diagnosis as the AI patterns may aid in the identification of clinically significant correlations between symptoms, behaviors, and indications. Canvas Dx is the US FDA-approved medical device that helps physicians in diagnosing autism spectrum disorder in children aged between 18-72 months. In Jun 2022, Cognoa reported the initiation of a real-world evidence study for Canvas Dx in collaboration with the University of Missouri ECHO Autism Communities Research Team.

 

Founded Year: 2014

Total Employees: ~500

Headquarters: Tokyo, Japan

Therapy Areas: Lifestyle Diseases, Neurology

CureApp is a healthcare company that develops and delivers digital therapeutics in the form of treatment apps to manage addiction and health vitals. The company leverages digital technologies to develop software used for the treatment of lifestyle diseases like smoking cessation and neurological conditions like hypertension. The application allows an analysis of the patient’s daily data obtained through smartphones and other devices and provides personalized treatment intervention for each patient based on their data. In May 2022, CureApp’s digital therapeutic app for Hypertension was approved by the medical device regulatory body in Japan.

 

Founded Year: 2011

Total Employees: ~240

Headquarters: New York, United States

Therapy Areas: Metabolic, Musculoskeletal, Neurology

Striving to provide digital therapeutics for patients with chronic conditions, DarioHealth has marked its position among the companies developing software-based therapies. The company develops and delivers personalized data analytics and one-on-one coaching for patients with Diabetes, Hypertension, Weight Management, Musculoskeletal Pain, and Behavioral Health. Dario Evolve, Dario Move, Dario Elevate, and Dario One are some of the digital offerings provided by the company. In Jan 2022, DarioHealth acquired Physimax Technologies, a provider of computer vision (CV) technology for Musculoskeletal function screening and predictive risk of injury assessment.

 

Founded Year: 2009

Total Employees: ~200

Headquarters: Queensland, Australia

Therapy Areas: Infectious Diseases

Addressing the needs of patients suffering from infectious diseases, Ellume is a healthcare company that develops, manufactures, and commercializes digital diagnostics to ease the diagnostic process for healthcare professionals and consumers. The company integrates diagnostic technology with smart devices and software to deliver a range of diagnostic tests at point-of-care and higher-throughput laboratories. QIAreach SARS-CoV-2 Antigen Tests, Influenza Home Test, COVID-19 Home Test, and ellume·lab are the products developed by the company. On Jan 2022, Ellume reported that its QIAreach QuantiFERON-TB test was approved by the Global Fund’s Expert Review Panel for Diagnostics for the detection of Tuberculosis.

 

Founded Year: 2010

Total Employees: ~200

Headquarters: California, United States

Therapy Areas: Metabolic, Endocrine

Glooko is a healthcare company that provides personalized connected care platforms for patients suffering from chronic conditions. The company mainly focuses on developing therapies for the diagnosis and treatment of diabetes through its software platforms that allow the management of diabetes and related conditions. Accu-Chek Active, Dexcom G4 Platinum, Apple Health, Fitbit, Accu-Chek Aviva Insight, and Novopen 6 are among the many products developed by the company. In Jan 2022, Glooko acquired xbird, an AI company developing JITAI (Just in Time Adaptive Intervention) technologies, to enhance its digital health capabilities with machine learning.

 

Founded Year: 2016

Total Employees: ~200

Headquarters: Munich, Germany

Therapy Areas: Musculoskeletal, Pulmonary, Neurology

Kaia Health is a healthcare company that develops and commercializes digital therapeutics to treat musculoskeletal conditions (back, hip, and knee pain) and COPD. These therapies are developed using artificial intelligence, computer vision, and the expertise of medical experts. The company has broadened its range of therapies to include Neurology as they are currently evaluating digital therapies for the treatment of Parkinson’s Disease. In Apr 2022, Kaia Health and UnitedHealthcare launched a Virtual Physical Therapy program for patients with musculoskeletal issues that could benefit from physical therapy support.

 

Founded Year: 2011

Total Employees: ~200

Headquarters: California, United States

Therapy Areas: Chronic Diseases

Inspired by a vision to develop an AI-based chronic disease management platform, Lark Health is a healthcare company that focuses on Diabetes, Hypertension, and Behavioural Health. The company provides digitalized solutions with AI coaching, smart devices, and telemonitoring. The company provides personalized coaching on food, activity, sleep, and weight to tailor digital therapies according to the patient’s needs. In Mar 2022, Lark Health in collaboration with Roche Diagnostics reported the development of an AI-driven program for the prevention and management of Atherosclerotic Cardiovascular Disease (ASCVD) and Coronary Artery Disease (CAD).

 

Founded Year: 2008

Total Employees: ~5,000

Headquarters: New York, United States

Therapy Areas: Metabolic, Endocrine, Neurology

Noom Health is a digital healthcare company that develops and delivers digital therapies for weight management and behavioral changes. The digital solutions provided by the company are integrated with artificial intelligence, mobile technology, and the psychological inputs of several personal coaches. The company initially began by guiding patients with weight management but is now expanding its business into providing behavior-change platforms for the treatment of many chronic and non-chronic diseases, including Stress, Anxiety, Hypertension, and Diabetes. In Nov 2022, Noom Health reported the launch of its ‘Noom for Work’ digital business-to-business offering across North America for the well-being of employees and to enhance productivity while reducing healthcare costs.

 

Founded Year: 2011

Total Employees: ~680

Headquarters: California, United States

Therapy Areas: Prevention, Diabetes, Hypertension, Musculoskeletal

A digital healthcare firm, Omada Health offers inducive digital treatments for conditions like Diabetes, Hypertension, and Musculoskeletal Disorders. The company provides mobile apps for behavior modification to prevent chronic diseases. Combining the latest clinical protocol with behavioral science is how the company helps its consumers reduce the risk of chronic diseases. In Feb 2023, Omada Health reported a $192M Series E funding led by Fidelity Management & Research Company with participation from aMoon and its existing investors. 

 

Founded Year: 2015

Total Employees: ~200

Headquarters: New York, United States

Therapy Areas: Metabolic, Endocrine

A precision digital health company, One Drop delivers digital therapies for the treatment of patients with diabetes and other chronic conditions. The company provides a diabetes management platform through a mobile app developed using behavioral science, mobile computing, and data science. The mobile app allows patients with Type 1/2 or pre-diabetes to track their glucose levels, diet, activity, and insulin levels and thereby allows the user to be proactive. In Apr 2022, One Drop presented the clinical data from the study evaluating the long-term use of its digital platform in patients suffering from diabetes at the ATTD 2022.

 

Founded Year: 2013

Total Employees: ~250

Headquarters: Massachusetts, United States

Therapy Areas: Neurology

With its pursuit to develop and deliver digitalized therapies, Pear Therapeutics is a renowned name among healthcare companies. These digitalized software-based medicines are called Prescription Digital Therapeutics (PDTs). The company leverages clinically validated software-based therapeutics to provide better treatment outcomes under its main target therapy area, Neurology. In Mar 2022, Pear announced the extension of its telehealth program for patients with QuickMD, its second telehealth service, which offers consultation and urgent treatment over the phone and via video.

 

Founded Year: 1989

Total Employees: ~8,160

Headquarters: California, United States

Therapy Areas: Neurology, Respiratory

ResMed is a digital health and cloud-connected medical device company that develops innovative solutions. The company’s innovative solutions are designed to treat patients with Sleep Apnea, Chronic Obstructive Pulmonary Disease, COPD, or other chronic diseases. Their software platforms are designed to support professionals and caregivers in providing treatment from the comfort of a patient's home or care setting of a patient’s choice. In Nov 2022, ResMed reported the completion of its $958.6M acquisition of Medifox Dan, an out-of-hospital care management software solutions company. 

 

Founded Year: 2015

Total Employees: ~500

Headquarters: New York, United States

Therapy Areas: Musculoskeletal

Sword Health focuses on developing and delivering digital therapies designed through clinical expertise and artificial intelligence. The company uses FDA-listed wearable technology to create a personalized treatment plan for a more efficient, simple, and affordable treatment option, thereby offering a digital substitute for conventional physical therapy. Its Physical Therapist Portal provides reviews by the Physical Therapists, tailored treatment plans, and thorough communication with patients. In Aug 2022, Sword Health entered a collaboration with Verily’s Onduo to accelerate the adoption of a comprehensive precision care approach by offering complementary solutions to each of the company’s employer customer and their employees.

 

Founded Year: 2014

Total Employees: ~500

Headquarters: Colorado, United States

Therapy Areas: Endocrine, Metabolic, Cardiovascular

Virta Health develops and delivers digital therapies for the reversal of type 2 diabetes, prediabetes, or obesity. The company leverages innovation in technology, nutrition science, and continuous remote care from physicians and behavioral experts to reverse type 2 diabetes along with other chronic conditions. The company provides medical care to patients through its custom-designed app and medical records system guided by its technology, physicians, nurse practitioners, and coaches. In Aug 2022, Virta Health entered a collaboration with Quartz Partners for its Type 2 Diabetes and Obesity solutions to improve patient health with personalized goals.

Related Post: Top Innovative Digital Therapeutics Companies of 2021


Shivani Chandra

Shivani was a content writer at PharmaShots. She has a keen interest in recent innovations in the life sciences industry. She was covering news related to Product approvals, clinical trial results, and updates. We can be contacted at connect@pharmashots.com.

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